Application Note 104:
Headspace oxygen monitoring and container closure integrity testing of pre-filled syringes


This Application Note describes rapid non-destructive headspace oxygen monitoring in syringes having a purged headspace. Case study data is presented for important applications: 1) headspace oxygen monitoring during the filling of oxygen-sensitive product; 2) stability and end-of-shelf-life testing; 3) container closure testing.

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Other interesting topics

Download the Lighthouse Brochure

Download the White Paper: "Introduction to Laser-Based Headspace Inspection and the Application to 100% Container Closure Inspection of Sterile Pharmaceutical Containers"”

Download the Application Note “Stopper Pop-Up and the Effects on Container Closure of Sterile Vials

Download the Application Note “In-process Monitoring of Headspace Oxygen Levels in Parenteral Containers"

Download the poster “Non-Destructive Monitoring of Oxygen in Pre-Filled Syringes

Download the White Paper "Using Laser-Based Headspace Moisture Analysis for Rapid Nondestructive Moisture Determination of Sterile Freeze-Dried Product"



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